Publications

A.E. Draghici, G. Picard, J.A. Taylor, S.J. Shefelbine, (2017). Assessing kinematics and kinetics of functional electrical stimulation rowing. Journal of Biomechanics, 28(53):120-126.

A.K. Oestreich, M.R. Garcia, X. Yao, F.M. Pfeiffer, S. Nobakhti, S.J. Shefelbine, ... & C.L. Phillips, (2015). Characterization of the MPS IH knock-in mouse reveals increased femoral biomechanical integrity with compromised material strength and altered bone geometry. Molecular Genetics and Metabolism Reports 5: 3-11.

O.G. Andriotis, S.W. Chang, M. Vanleene, P.H. Howarth, D.E. Davies, S.J. Shefelbine, M.J. Buehler, & P.J. Thurner, (2015). Structure-mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model. Journal of the Royal Society, Interface/ the Royal Society 12: 111.

A.F. Pereira, B. Javaheri, A.A. Pitsillides, & S.J. Shefelbine, (2015). Predicting cortical bone adaptation to axial loading in the mouse tibia. Journal of the Royal Society, Interface / the Royal Society 12: 110.

B. Javaheri, A. Carriero, K.A. Staines, Y.M. Chang, D.A. Houston, K.J. Oldknow, J.L. Millán, B.N. Kazeruni, P. Salmon, S.J. Shefelbine, C. Farquharson, & A.A. Pitsillides, (2015). Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing. Bone 81: 277-91.

M. Giorgi, A. Carriero, S.J. Shefelbine, & N.C. Nowlan, (2015). Effects of normal and abnormal loading conditions of morphogenesis of the prenatal hip joint: application to hip dysplasia. Journal of Biomechanics, 48: 12.

M.M. Klosowki, R.J. Friederichs, R. Nichol, N. Antolin, R. Carzaniga, W. Windl, S.M. Best, S.J. Shefelbine, D.W. McComb, & A.E. Porter, (2015). Probing carbonate in bone forming materials on the nanometre scale. Acta Biomaterialia, 20: 129- 139.

J.P. Berteau, M. Oyen, & S.J. Shefelbine, (2015). Permeability and shear modulus of articular cartilage in growing mice. Biomechanics and Modeling in Mechanobiology 1-8.

R.E. Horenstein, S.J. Shefelbine, N.M. Mueske, C.L. Fisher and T.A. Wren, (2015). An approach for determining quantitative measures for bone volume and bone mass in the pediatric spina bifida population. Clin Biomech 30(7): 748–754.

A. Carriero, J.L. Bruse, K.J. Oldknow, J.L> Millán, C. Farquharson, & S.J. Shefelbine, (2014). Reference point indentation is not indicative of whole mouse bone measures of stress intensity fracture toughness. Bone 69: 174-9.

B. Depalle, Z. Qin, S.J. Shefelbine, & M.J. Buehler, (2014). Influence of cross-link structure, density and mechanical properties in the mesoscale deformation mechanisms of collagen fibrils. Journal of the Mechanical Behavior of Biomedical Materials 52:1-13.

A. Carriero, E.A. Zimmerann, S.J. Shefelbine, & R.O. Ritchie, (2014). A methodology for the investigation of toughness and crack propagation in a mouse bone. Jouranl of the Mechanical Behavior of Biomedical Physics 39: 38-47.

J.P. Berteau, M. Oyen, S. Shefelbine, (2014). In vitro characterization of the elasticity and the permeability of the mouse cartilage during growth using microindentation. Computer Methods in Biomechanics and Biomedical Engineering 17: 68-9.

N. Rodriguez-Florez, E. Garcia-Tunon, Q. Mukadam, E. Saiz, K.J. Oldknow, C. Farquharson, J.L. Millán, A. Boyde and S.J. Shefelbine, (2014). An investigation of the mineral in ductile and brittle cortical mouse bone. J Bone Miner. Res. 30(5): 786–795.

A. Carriero, L. Abela, A.A. Pitsillides, S.J. Shefelbine, (2014). Ex vivo determination of bone tissue strains for an in vivo mouse tibial loading model. J of Biomechanics 47(10): 2490-7.

M. Giorgi, A. Carriero, S.J. Shefelbine, N.C. Nowlan, (2014). Mechanobiological simulations of prenatal joint morphogenesis. J of Biomechanics 47(5): 989-95.

N. Rodriguez-Florez, M.L. Oyen, S.J. Shefelbine, (2014). Age related changes in mouse bone permeability. J of Biomechanics 47(5): 1110-16.

G.N. Jones, D. Moschidou, H. Abdulrazzak, B.S. Kalirai, M. Vanleene, S. Osatis, S.J. Shefelbine, N.J. Horwood, M. Marenzana, P. De Coppi, J.H. Bassett, G.R. Williams, N.M. Fisk, P.V. Guillot, (2014). Potential of human fetal chorionic stem cells for the treatment of osteogenesis imperfecta. Stem Cells Dev 23(3): 262-76.

A. Carriero, E.A. Zimmermann, A. Paluszny, S.Y. Tang, H. Bale, B. Busse, T. Alliston, G. Kazakia, R.O. Ritchie, S.J. Shefelbine, (2014). How tough is Brittle Bone? Investigating Osteogenesis Imperfecta in Mouse Bone. J Bone Miner Res 29(6): 1392–1401.

A. Carriero, M. Doube, M. Vogt, B. Busse, J. Zustin, A. Levchuk, P. Schneider, R. Müller and S.J. Shefelbine, (2014). Altered lacunar and vascular porosity in osteogenesis imperfecta mouse bone as revealed by synchrotron tomography contributes to bone fragility. Bone 61:116-24.

A. Pereira, S.J. Shefelbine, (2014). The influence of load repetition in bone mechanotransduction using poroelastic finite element models: The impact of permeability. Biomechanics and Modeling in Mechanobiology 13(1): 215-25.

W. Macdonald and S.J. Shefelbine, (2013). Characterising neovascularisation in fracture healing with laser Doppler and micro-CT scanning. Med Biol Eng Comput 51: 1157-65.

M. Vanleene, S. J. Shefelbine, (2013). Therapeutic impact of low amplitude high frequency whole body vibrations on the osteogenesis imperfecta mouse bone. Bone 53(2): 507-14

B. Poulet, T.A.T. Westerhof, R. Hamilton, S.J. Shefelbine, A.A. Pitsillides, (2013). Spontaneous osteoarthritis in Str/ort mice is unlikely due to greater vulnerability to mechanical trauma. Osteoarthritis and Cartilage 21(5): 756-63.

N. Rodriguez, M. L. Oyen, S. J. Shefelbine, (2013). Insight into differences in nanoindentation properties of bone. J Mech Behavior of Biomed Mater 18: 90-9.

G.N. Jones, D. Moschidou, K. Lay, H. Abdulrazzak, M. Vanleene, S. J. Shefelbine, J. Polak, P. de Coppi, N.M. Fisk, P.V. Guillot, (2012) Upregulating CXCR4 in human fetal mesenchymal stem cells enhances engraftment and bone mechanics in a mouse model of osteogenesis imperfecta. Stem Cell Translational Medicine 1: 70-8.

G.N. Jones, D. Moschidou, T.I. Puga-Iglesias, K. Kuleszewicz, M. Vanleene, S. J. Shefelbine, G. Bou-Gharios, N.M. Fisk, A.L. David, P. de Coppi, P.V. Guillot, (2012). Ontological differences in first compared to third trimester human fetal placental chorionic stem cells. PloS One: 7(9): e43395.

M. Doube, S.C.W. Yen, M.M. Klosowski, A.A. Farke, J.R. Hutchinson, S. J. Shefelbine, (2012). Whole-bone scaling of the avian pelvic limb. J Anatomy 221(1): 21-9.

Carriero, A. Zavatsky, J. Stebbins, T. Theologis, G. Lenaerts, I. Jonkers, and S. J. Shefelbine, (2012). Influence of altered gait patterns on the hip joint contact forces. Comput Meth in Biomech and Biomed Eng 17: 352-59.

K.Y. Zhang, A. Wiktorowicz-Conroy, J.R. Hutchinson, M. Doube, M.M. Klosowski,S. J. Shefelbine, A.M.J. Bull, (2012). 3D morphometric and posture study of felid scapulae using statistical shape modelling. PLoS One.2012;7(4): e34619

M. Vanleene, A. Porter, P. Guillot, A. Boyde, M. Oyen, and S. J. Shefelbine, (2012). Ultra-structural defects cause low bone matrix stiffness despite high mineralization in osteogenesis imperfecta mice. Bone 50(6):1317-23

S. Cheng, S. J. Shefelbine, and M. Buehler, (2012). Structural and mechanical differences between collagen homo- and heterotrimers: General insight and relevance for brittle bone disease. Biophysical Journal 102(3): 640-8.

O. Panagiotopoulou, S. Wilshin, E. Rayfield, S. J. Shefelbine, J. R. Hutchinson, (2011). What makes an accurate and reliable subject-specific finite element model? A case study of an elephant femur. J Royal Society Interface 9:351-61.

M. Doube, M Kłosowski, A. M. Wiktorowicz-Conroy, J. R. Hutchinson, S. J. Shefelbine, (2011). Trabecular bone scales allometrically in mammals and birds. Proceedings of the Royal Society Biology B 278:3067-73.

J. P. Moodie, K. S.Stok, R. Müller, T. L.Vincent, S. J. Shefelbine, (2011). Multimodal imaging demonstrates concomitant changes in bone and cartilage after destabilisation of the medial meniscus and increased joint laxity. Osteoarthritis and Cartilage 19(2): 163-70.

M. Vanleene, Z. Saldanha, K. L. Cloyd, G. Jell, G. Bou-Gharios, J. H. D. Bassett, G. R. Williams, N. M. Fisk, M. L. Oyen, M. M. Stevens, P. V. Guillot, S. J. Shefelbine, (2011). Transplantation of human fetal blood stem/stromal cells in the osteogenesis imperfecta mouse leads to improvement in multi-scale tissue properties. Blood 117(3): 1053-60.

M. Doube, M. M. Kłosowski, I. Arganda-Carreras, F. P. Cordelières, R. P. Dougherty, J. S. Jackson, B. Schmid, J. R. Hutchinson, S. J. Shefelbine, (2010). BoneJ: Free and extensible bone image analysis in ImageJ. Bone 47(6): 1076-9.

B. Poulet, R. W. Hamilton, S. J. Shefelbine, A. A. Pitsillides, (2010). Characterising a novel and adjustable non-invasive murine knee joint loading model. Arthritis Rheum. 63(1): 137-4.

A. Carriero, I. Jonkers, S. J. Shefelbine, (2010). Mechanobiological prediction of proximal femoral deformities in children with cerebral palsy. Computer Methods and Biomedical Engineering 14(3): 253-62

P. Sztefek, M. Vanleene, R. Olsson, R. Collinson, A. A. Pitsillides, S. J. Shefelbine, (2010). Using digital image correlation to determine surface strains during loading and after adaptation of the mouse tibia. Journal of Biomechanics 43: 599-605.

M. Doube, A. Wiktorowicz Conroy, P. Christiansen, JR Hutchinson, S. J. Shefelbine, (2009). Three-dimensional geometric analysis of felid limb bone allometry. Public Library of Science (PLoS) One. 4(3) e4742. (link to pdf)

A. Carriero, A. Zavatsky, J. Stebbins, T. Theologis, S. J. Shefelbine, (2009). Correlation between lower limb bone morphology and gait characteristics in children with spastic diplegic cerebral palsy. Journal of Paediatric Orthopaedics. 29(1):73-9.

A. Carriero, A. Zavatsky, J. Stebbins, T. Theologis, S. J. Shefelbine, (2009). Determination of gait patterns in children with spastic diplegic cerebral palsy using principal components. Gait and Posture. 29(1):71-5.

R. D. Carpenter, S. J. Shefelbine, J. Lozano, K.Y. Lee, S. Majumdar, B. Ma, (2008). A New Device for Measuring Knee Rotation in ACL-Deficient Patients. Journal of Medical Devices, 2: 44501-1.

P.V. Guillot, O. Abass, J.H. Bassett, S.J. Shefelbine, G. Bou-Gharios, J. Chan, H. Kurata, G.R. Williams, J. Polak, N.M. Fisk, (2008). Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice. Blood, 111: 1717 – 1725.

S. J. Shefelbine, S. Majumdar, (2005). Imaging bone structure and osteoporosis using MRI. Clincal Cases in Min and Bone Metabolism 2(2):119-26.

S. J. Shefelbine, B. Ma, K.Y. Lee, M.A. Schrumpf, P. Patel, M.R. Safran, J.P. Slavinsky, S. Majumdar, (2006). MRI Analysis of in vivo meniscal and tibiofemoral kinematics in ACL-deficient and normal knees. Journal of Orthpaedic Research. 24(6): 1208-17.

Sarkar, M. R., P. Augat, S.J. Shefelbine, S. Schorlemmer, M. Huber-Lang, L. Claes, L. Kinzl, A. Ignatius, (2005). Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold. Biomaterials 27(9): 1817-23.

S. J. Shefelbine, P. Augat, L. Claes, and U. Simon, (2005). Trabecular bone fracture healing simulation with finite element analysis and fuzzy logic. Journal of Biomechanics 38(12): 2440-50.

S. J. Shefelbine, P. Augat, L. Claes, A. Gold, Y. Gabet, I. Bab, and R. Müller, (2005). Prediction of fracture callus mechanical properties using microCT images and finite element analysis. Bone 36(3): 480-8.

S. J. Shefelbine, P. Augat, L. Claes, and A. Beck, (2005). Intact fibula improves fracture healing in a rat tibia osteotomy model. Journal of Orthopaedic Research 23(2): 489-93.

S. J. Shefelbine and D. R. Carter, (2004). Mechanobiological predictions of femoral anteversion in cerebral palsy. Annals of Biomedical Engineering. 32(2): 297-305.

S. J. Shefelbine and D. R. Carter, (2004). Mechanobiological predictions of growth front morphology in developmental hip dysplasia. Journal of Orthopedic Research 22(2): 346-52.

S. J. Shefelbine, C. Tardieu, and D. R. Carter, (2002). Development of the femoral bicondylar angle in hominid bipedalism. Bone 30(5): 765-70.


Books


A.E. Draghici, S.J. Shefelbine, (2016). Increased Bone Fracture After SCI: Can Exercise Reduce Risk? The Physiology of Exercise in Spinal Cord Injury, 161-174.

S. J. Shefelbine, J. Clarkson, R. Farmer, S. Eason. Good design practice for medical devices and equipment – requirements capture. Institute for Manufact